Animal-Free Recombinant Human IFN-γ
Catalog Number:
AF-300-02
Synonyms:
Immune Interferon, type II interferon, T cell interferon, MAF
重组人干扰素γ详细描述如下：
IFN-γ是由CD4和CD8 T淋巴细胞以及活化NK细胞产生的酸不稳定干扰素。IFN-γ受体存在于大多数免疫细胞，其响应通过增加I类MHC蛋白的表面表达，以IFN-γ信号传导。这促进了抗原与T-辅助（CD4+）细胞的呈现。的IFN-γ的抗原呈递细胞信令和识别抗原的B和T淋巴细胞，调节免疫应答的抗原特异性相。此外，IFN-γ刺激了许多淋巴样细胞的功能，包括巨噬细胞，NK细胞和嗜中性粒细胞的抗微生物和抗肿瘤应答。人IFN-γ是物种特异性的，具有生物活性仅在人类和灵长类动物细胞。重组人IFN-γ的是含有144个氨基酸残基16.8 kDa的蛋白质。Manufactured using all Animal-Free reagents.
Animal-Free Recombinant Human IFN-γ Description:
IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells, and antigen-recognizing B and T lymphocytes, regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions, including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ is species-specific and is biologically active only in human and primate cells. Recombinant Human IFN-γ is a 16.8 kDa protein containing 144 amino acid residues. Manufactured using all Animal-Free reagents.
AA Sequence:
MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFQGR RASQ
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Animal-Free Recombinant Human IFN-γ订购信息如下：
Animal Free Recombinant Protein AF-300-02 AF-300-02-100 Human IFN-gamma 100ug Standard
Animal Free Recombinant Protein AF-300-02 AF-300-02-250 Human IFN-gamma 250ug Bulk
Animal Free Recombinant Protein AF-300-02 AF-300-02-500 Human IFN-gamma 500ug Bulk
Animal Free Recombinant Protein AF-300-02 AF-300-02-1000 Human IFN-gamma 1000ug Bulk
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